On Phosphine-containing Gold(I) Complexes in Solution and Their Biological Application

On Phosphine-containing Gold(I) Complexes in Solution and Their Biological Application Full article

Journal

Russian Journal of Inorganic Chemistry
ISSN: 0036-0236 , E-ISSN: 1531-8613

Output data

Year: 2024, Volume: 69, Pages: 907–913 Pages count : DOI: 10.1134/S0036023624600965

Tags

gold(I) compounds, phosphines, complexation, thiols

Authors

Mironov I.V. ¹ , Kharlamova V.Yu. ¹ , Kal'nyi D.B. ¹

Affiliations

1	Nikolaev Institute of Inorganic Chemistry, Siberian Branch, Russian Academy of Sciences

Some transformations involving AuCl(PPh3) in CH3CN/H2O solution are considered and compared with data known for auranofin. The reaction with GSH leads to the formation of binuclear complex (GSH)[Au(PPh3)](2) (at C-GSH/C-Au < 0.5) or mononuclear complex Au(GSH)(PPh3) (C-GSH/C-Au > 0.5); PPh3 substitution is not observed. The reaction with BSA leads to Cl- substitution. A cyclic voltammetry study showed the presence of several peaks of irreversible oxidation of AuCl(PPh3) and complexes with GSH.

Mironov I.V. , Kharlamova V.Y. , Kal'nyi D.B.
On Phosphine-containing Gold(I) Complexes in Solution and Their Biological Application
Russian Journal of Inorganic Chemistry. 2024. V.69. P.907–913. DOI: 10.1134/S0036023624600965 WOS Scopus РИНЦ OpenAlex

Миронов И.В. , Харламова В.Ю. , Кальный Д.Б.
О фосфинсодержащих комплексах золота(I) в растворе в связи с их биологическим применением
Журнал неорганической химии. 2024. Т.69. №6. С.899-906. DOI: 10.31857/S0044457X24060129 РИНЦ OpenAlex

Submitted:	Dec 12, 2023
Accepted:	Mar 13, 2024
Published print:	Aug 9, 2024
Published online:	Aug 16, 2024

Web of science:	WOS:001288090700009
Scopus:	2-s2.0-85200998569
Elibrary:	73260750
OpenAlex:	W4401455915

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