On Phosphine-containing Gold(I) Complexes in Solution and Their Biological Application

On Phosphine-containing Gold(I) Complexes in Solution and Their Biological Application Научная публикация

Журнал

Russian Journal of Inorganic Chemistry
ISSN: 0036-0236 , E-ISSN: 1531-8613

Вых. Данные

Год: 2024, DOI: 10.1134/S0036023624600965

Ключевые слова

gold(I) compounds, phosphines, complexation, thiols

Авторы

Mironov I.V. ¹ , Kharlamova V.Yu. ¹ , Kal'nyi D.B. ¹

Организации

1	Nikolaev Institute of Inorganic Chemistry, Siberian Branch, Russian Academy of Sciences

Some transformations involving AuCl(PPh3) in CH3CN/H2O solution are considered and compared with data known for auranofin. The reaction with GSH leads to the formation of binuclear complex (GSH)[Au(PPh3)](2) (at C-GSH/C-Au < 0.5) or mononuclear complex Au(GSH)(PPh3) (C-GSH/C-Au > 0.5); PPh3 substitution is not observed. The reaction with BSA leads to Cl- substitution. A cyclic voltammetry study showed the presence of several peaks of irreversible oxidation of AuCl(PPh3) and complexes with GSH.

Mironov I.V. , Kharlamova V.Y. , Kal'nyi D.B.
On Phosphine-containing Gold(I) Complexes in Solution and Their Biological Application
Russian Journal of Inorganic Chemistry. 2024. DOI: 10.1134/S0036023624600965 WOS Scopus РИНЦ OpenAlex

Миронов И.В. , Харламова В.Ю. , Кальный Д.Б.
О фосфинсодержащих комплексах золота(I) в растворе в связи с их биологическим применением
Журнал неорганической химии. 2024. Т.69. №6. С.899-906. DOI: 10.31857/S0044457X24060129

Поступила в редакцию:	12 дек. 2023 г.
Принята к публикации:	13 мар. 2024 г.
Опубликована в печати:	9 авг. 2024 г.
Опубликована online:	16 авг. 2024 г.

Web of science:	WOS:001288090700009
Scopus:	2-s2.0-85200998569
РИНЦ:	73260750
OpenAlex:	W4401455915

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