Ruthenium Nitrosyl Complexes with Bidentate Heterocycles and Chloride Ligands: Synthesis and Photorelease of NO

Ruthenium Nitrosyl Complexes with Bidentate Heterocycles and Chloride Ligands: Synthesis and Photorelease of NO Научная публикация

Журнал

International Journal of Molecular Sciences
ISSN: 1661-6596 , E-ISSN: 1422-0067

Вых. Данные

Год: 2026, Том: 27, Номер: 14, Номер статьи : 6172, Страниц : 12 DOI: 10.3390/ijms27146172

Ключевые слова

ruthenium nitrosyl; nitric oxide release; photochemistry; ruthenium complex

Авторы

Brovko Anastasia O. ¹ , Yakovlev Ivan A. ¹ , Kuratieva Natalia V. ^1,2 , Sheven Dmitriy G. ¹ , Kostin Gennadiy A. ¹

Организации

1	Nikolaev Institute of Inorganic Chemistry, Siberian Branch of the Russian Academy of Sciences, 3 Acad. Lavrentiev Avenue, 630090 Novosibirsk, Russia
2	N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 Acad. Lavrentiev Avenue, 630090 Novosibirsk, Russia

Информация о финансировании (1)

Российский научный фонд

A set of new coordination compounds of the formula [RuNO(L)Cl3], with L representing the bidentate ligands bipyrimidine (bpym), bipyridine (bpy), or phenanthroline (phen), was prepared and fully characterized. For the isomeric species fac-[RuNO(bpym)Cl3] (1), fac-[RuNO(phen)Cl3] (2), mer-[RuNO(phen)Cl3] (3), fac-[RuNO(bpy)Cl3] (4), and mer-[RuNO(bpy)Cl3] (5), an evaluation of the photoresponse in DMSO was performed under excitation with 450 nm using a continuous-flow arrangement that enabled the simultaneous acquisition of IR and UV-Vis spectral data. Quantum yields for photoinduced release of NO were determined as follows: 5.4 ± 0.5% for fac-[RuNO(bpym)Cl3] (1); 0.8 ± 0.1% for fac-[RuNO(phen)Cl3] (2); 0.6 ± 0.1% for mer-[RuNO(phen)Cl3] (3); 3.7 ± 0.1% for fac-[RuNO(bpy)Cl3] (4); 2.1 ± 0.1% for mer-[RuNO(bpy)Cl3] (5). The product of the photolysis of compound 5 in acetonitrile solution was isolated and structurally characterized as mer-[Ru(CH3CN)(bpy)Cl3] (6). Taking into account the presence of typical DNA intercalating ligands, the complexes can be potentially exploited as photoNORMs.

Brovko A.O. , Yakovlev I.A. , Kuratieva N.V. , Sheven D.G. , Kostin G.A.
Ruthenium Nitrosyl Complexes with Bidentate Heterocycles and Chloride Ligands: Synthesis and Photorelease of NO
International Journal of Molecular Sciences. 2026. V.27. N14. 6172 :1-12. DOI: 10.3390/ijms27146172

Поступила в редакцию:	1 июл. 2026 г.
Опубликована в печати:	10 июл. 2026 г.

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