Synthesis and Properties of Iron(II) and Copper(II) Coordination Compounds with 2,6-Bis[1-(phenylimino)ethyl]pyridine

Synthesis and Properties of Iron(II) and Copper(II) Coordination Compounds with 2,6-Bis[1-(phenylimino)ethyl]pyridine Full article

Journal

Russian Journal of General Chemistry
ISSN: 1070-3632 , E-ISSN: 1608-3350

Output data

Year: 2021, Volume: 91, Number: 11, Pages: 2167–2175 Pages count : DOI: 10.1134/S1070363221110062

Tags

complexes, iron(II), copper(II), 2,6-bis[1-(phenylimino)ethyl]pyridine, magnetic and cytotoxic activity

Authors

Lavrenova L.G. ¹ , Mishchenko А.А. ^1,2 , Oleynik I.V. ³ , Korotaev E.V. ¹ , Lavrov A.N. ¹ , Grebenkina M.A. ^1,2 , Sheludyakova L.A. ¹ , Klyushova L.S. ⁴ , Oleynik I.I. ³

Affiliations

1	A.V. Nikolaev Institute of Inorganic Chemistry, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090 Russia
2	Novosibirsk National Research State University, Novosibirsk, 630090 Russia
3	N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090 Russia
4	Institute of Molecular Biology and Biophysics, Federal Research Center for Fundamental and Translational Medicine, Novosibirsk, 630117 Russia

New iron(II) and copper(II) coordination compounds with 2,6-bis[1-(phenylimino)ethyl]pyridine (L1), Fe(L1)2SO4·H2O, Fe(L1)2(ClO4)2, Cu(L1)Cl2, and Cu(L1)2Br2·2H2O, were synthesized. The compounds were identified and investigated using CHN analysis and electronic spectroscopy (diffuse reflectance spectroscopy), IR spectroscopy, XRD, and static magnetic susceptibility. Antiferromagnetic exchange interactions between paramagnetic centers are observed in all iron and copper complexes in the ranges 80–420 and 1.77–300 K, respectively. Evaluation of the cytotoxic activity of copper(II) complexes showed that the Cu(L1)2Br2 complex (IC50 26.7 μmol/L) exhibits the highest activity against the human breast adenocarcinoma cell line (MCF-7).

Lavrenova L.G. , Mishchenko А.А. , Oleynik I.V. , Korotaev E.V. , Lavrov A.N. , Grebenkina M.A. , Sheludyakova L.A. , Klyushova L.S. , Oleynik I.I.
Synthesis and Properties of Iron(II) and Copper(II) Coordination Compounds with 2,6-Bis[1-(phenylimino)ethyl]pyridine
Russian Journal of General Chemistry. 2021. V.91. N11. P.2167–2175. DOI: 10.1134/S1070363221110062 WOS Scopus РИНЦ OpenAlex

Web of science:	WOS:000731285100006
Scopus:	2-s2.0-85121453593
Elibrary:	47546595
OpenAlex:	W4200218596

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