Реферат: Nickel(II) complexes with the simple N4 donor aminopyridine ligands BPMEN (N,N′-dimethyl-N,N′-bis(2-pyridylmethyl)-1,2-diaminoethane) and TPA (tris(2-pyridylmethyl)amine) have been demonstrated to perform as efficient catalysts for the regioselective oxygenation of benzylic C−H groups with m-chloroperoxybenzoic acid under mild conditions (at 20 °C), typically ensuring >90 % substrate conversions within 1 h at 1 mol % catalyst loadings. Unprecedentedly, replacing the commonly used mixed reaction solvent CH3CN/CH2Cl2 with 2,2,2-trifluoroethanol diverts the selectivity of the above Ni-based catalyst systems from hydroxylation/ketonization to trifluoroalkoxylation, with the formation of 1-phenylalkyl 2,2,2-trifluoroethyl ethers. The use of 2,2,2-trifluoroethanol ensures high substrate conversion values (up to 97 %), as well as high selectivity for the ether formation (up to 92 %). Preliminary discussion of the reaction mechanism is given based on the catalytic and literature data.

Библиографическая ссылка: Bushmin D. , Samsonenko D. , Talsi E. , Lyakin O. , Bryliakov K.P.
Diverting Ni‐Catalyzed Direct Benzylic C−H Hydroxylation towards Trifluoroethoxylation
Chemcatchem. 2024. V.16. N7. e202301346 :1-8. DOI: 10.1002/cctc.202301346 WOS Scopus РИНЦ OpenAlex

Даты:

Поступила в редакцию:	23 окт. 2023 г.
Опубликована online:	27 нояб. 2023 г.
Опубликована в печати:	8 апр. 2024 г.

Идентификаторы БД:

Web of science:	WOS:001126771000001
Scopus:	2-s2.0-85179942824
РИНЦ:	62786343
OpenAlex:	W4389069716

Цитирование в БД:

БД	Цитирований
OpenAlex	3
Web of science	3
Scopus	3
РИНЦ	1

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